Genetic Analysis
Since the publication of DNA's double helical structure by Watson and Crick, electrophoresis has been a standard among the analytical tools used in
modern biochemistry. CE's automation and quantitation capabilities made it a natural successor to replace the slab-gel format for genetic analysis. By introducing replaceable physical gels (polymers in solution) into a capillary, a molecular sieve is created that readily resolves molecules of DNA and RNA by size. The automation capability of this format has enabled significant advances in genetic analysis, accelerating the discovery of new genomic information.
The Beckman Coulter CEQ 8000 and 8800 are fully automated genetic analysis systems that employ an array of coated capillaries, novel infrared dyes, an optimized linear polyacrylamide gel (LPA) and comprehensive informatics to fully automate the processes of DNA sequencing and genotyping. Plate bar coding and linkage to Beckman Coulter's Biomek liquid handlers provide efficient automation and sample tracking generating highly reproducible results. CE's simplicity of operation has moved the formerly complex genetic analysis tasks from the hands of a specialized few into the hands of many, enabling scientists to focus on the biology of interest rather than the technology
CGE separation of RNA molecules can be performed rapidly and in an
modern biochemistry. CE's automation and quantitation capabilities made it a natural successor to replace the slab-gel format for genetic analysis. By introducing replaceable physical gels (polymers in solution) into a capillary, a molecular sieve is created that readily resolves molecules of DNA and RNA by size. The automation capability of this format has enabled significant advances in genetic analysis, accelerating the discovery of new genomic information.
The Beckman Coulter CEQ 8000 and 8800 are fully automated genetic analysis systems that employ an array of coated capillaries, novel infrared dyes, an optimized linear polyacrylamide gel (LPA) and comprehensive informatics to fully automate the processes of DNA sequencing and genotyping. Plate bar coding and linkage to Beckman Coulter's Biomek liquid handlers provide efficient automation and sample tracking generating highly reproducible results. CE's simplicity of operation has moved the formerly complex genetic analysis tasks from the hands of a specialized few into the hands of many, enabling scientists to focus on the biology of interest rather than the technology
CGE separation of RNA molecules can be performed rapidly and in an
automated manner, allowing the user to quickly assess the quality of the RNA.
The P/ACE MDQ with laser-induced fluorescence detection is ideal for rapid, unattended profiling of up to 96 RNA samples per session with cycle times of less than five minutes per sample.
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